BDBM401214 3-[(5-Chloro-2-ethylsulfonylphenyl)methyl]-8-methyl-7-[[(3S)-3-(methylamino)piperidin-1-yl]methyl]-6-(trifluoromethyl)quinazolin-4-one::US10005739, Example 639

SMILES CCS(=O)(=O)c1ccc(Cl)cc1Cn1cnc2c(C)c(CN3CCC[C@@H](C3)NC)c(cc2c1=O)C(F)(F)F

InChI Key InChIKey=BNCCBSHDCKRQKL-IBGZPJMESA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 401214   

TargetEpithelial discoidin domain-containing receptor 1(Homo sapiens (Human))
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM401214(3-[(5-Chloro-2-ethylsulfonylphenyl)methyl]-8-methy...)
Affinity DataIC50:  31nMAssay Description:DDR1 binding activity was measured using the LanthaScreen (Registered trademark) Eu Kinase Binding Assay (manufactured by Life Technologies Corporati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent